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4. Možnost prodaje generičnih zdravil na trge Južne AmerikeSonja Engelman, 2006, undergraduate thesis Keywords: mednarodni trgi, prodaja, strategija prodaje, trženje zdravil, farmacevtska industrija, originalna zdravila, generična zdravila, licenčna zdravila, blagovna znamka, bioekvivalenčna raziskava, diplomska dela
Published in RUP: 15.10.2013; Views: 3455; Downloads: 114
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5. Od matematike do razvoja zdravilDušanka Janežič, 2012, review article Abstract: Razvoj novih zdravil je dolgotrajen in drag proces, saj celotni postopek od ideje do končnega izdelka običajno zahteva vsaj deset let raziskav in več kot milijardo dolarjev. Z uporabo novih matematičnih pristopov in modernih računalnikov skušamo skrajšati in poceniti predvsem zgodnje faze razvoja, pri čemer nas zanimajo tarčne biološke molekule, ki so vpletene v potek različnih bolezni. V Laboratoriju za molekularno modeliranje na Kemijskem inštitutu v Ljubljani razvijamo nova matematična orodja za uporabo na področju razvoja novih zdravil. Z algoritmi, ki temeljijo na teoriji grafov in metodah simulacije molekulske dinamike, preučujemo tarčne biološke molekule in pridobivamo pomembne podatke za optimiziranje zgodnjih stopenj razvoja novih zdravil.
Keywords: simulacija molekulske dinamike, teorija grafov, razvoj zdravil
Published in RUP: 15.10.2013; Views: 3626; Downloads: 43
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6. Prescribing of benzodiazepines among slovenian family physiciansMaja Šubelj, Gaj Vidmar, Vesna Švab, 2009, original scientific article Abstract: Background: In spite of their side effects, benzodiazepines are the most frequently prescribed psychotropic drugs in family medicine. The objective of this study was to investigate the possible association between physician characteristics, practice structure and practice population size with the pattern of prescribing benzodiazepines among Slovenian family physicians. Methods: We studied a representative sample of 100 family physicians using a combination of self-administered questionnaire, demographic data and data on prescribing provided by the Institute of Public Health of the Republic of Slovenia. The characteristics potentially influencing frequent prescribing were investigated by multiple linear regression analysis. Results: The estimated annual benzodiazepine consumption in Slovenia is nearly 3-fold lowerthan in the United Kingdom. Benzodiazepines were found to be less frequently prescribed by physicians with lower numbers of registered patients,as well as by female physicians, younger physicians, physicians followig the specialist training, those with short length of service, and by physicians working in large towns of the central healthcare region. The physicians' age and access to computerised decision-making support for drug management at the workplace were found to be significantly associated with increased prescription of benzodiazepines compared to the volume of prescribed psychotropic drugs. Conclusions: The results indicate that family physicians in Slovenia prescribe appropriate amounts of benzodiazepines. Benzodiazepines are less frequently prescribed in practices with less workload, by younger and female family physicians, in practices located in central Slovenia and by family physicians with online access to information at their workplace.
Keywords: zdravniki družinske medicine, predpisovanje zdravil, benzodiazepini
Published in RUP: 15.10.2013; Views: 5243; Downloads: 62
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