1. Maximal explosive power of the lower limbs before and after 35 days of bed rest under different diet energy intakeEnrico Rejc, Pietro Enrico Di Prampero, Stefano Lazzer, Bruno Grassi, Boštjan Šimunič, Rado Pišot, Guglielmo Antonutto, Marco Vincenzo Narici, 2015, original scientific article Keywords: maximal explosive power, bed rest, diet, lower limbs, nutritional countermeasures Published in RUP: 08.08.2016; Views: 2849; Downloads: 197 Link to full text |
2. Greater loss in muscle mass and function but smaller metabolic alterations in older compared to younger men following two weeks of bed rest and recoveryRado Pišot, Uroš Marušič, Gianni Biolo, Sara Mazzucco, Stefano Lazzer, Bruno Grassi, Carlo Reggiani, Luana Toniolo, Pietro Enrico Di Prampero, Angelina Passaro, Marco Vincenzo Narici, Shahid Mohammed, Joern Rittweger, Mladen Gasparini, Mojca Gabrijelčič Blenkuš, Boštjan Šimunič, 2016, original scientific article Keywords: ageing, prolonged physical inactivity, functional decline, reconditioning Published in RUP: 08.08.2016; Views: 3393; Downloads: 189 Link to full text |
3. A 35-day bed rest does not alter the bilateral deficit of the lower limbs during explosive effortsEnrico Rejc, Pietro Enrico Di Prampero, Stefano Lazzer, Bruno Grassi, Boštjan Šimunič, Rado Pišot, Guglielmo Antonutto, Marco Vincenzo Narici, 2015, original scientific article Keywords: bed rest, maximal explosive power, lower limbs, EMG, bilateral deficit Published in RUP: 08.08.2016; Views: 3151; Downloads: 293 Link to full text |
4. Skeletal muscle oxidative function in vivo and ex vivo in athletes with marked hypertrophy from resistance trainingDesy Salvadego, R. Domenis, Stefano Lazzer, Simone Porcelli, Joern Rittweger, Giovanna Rizzo, I. Mavelli, Boštjan Šimunič, Rado Pišot, Bruno Grassi, 2013, original scientific article Abstract: Oxidative function during exercise was evaluated in 11 young athletes with marked skeletal muscle hypertrophy induced by long-term resistance training (RTA, body mass 102.67.3 kg, meanSD) and 11 controls (CTRL, body mass 77.86.0). Pulmonary O2 uptake (V'O2) and vastus lateralis muscle fractional O2 extraction (by near-infrared spectroscopy) were determined during an incremental cycle ergometer (CE) and one-leg knee-extension (KE) exercise. Mitochondrial respiration was evaluated ex vivo by high-resolution respirometry in permeabilized vastus lateralis fibers obtained by biopsy. Quadriceps femoris muscle cross sectional area, volume (determined by magnetic resonance imaging) and strength were greater in RTA vs. CTRL (by ~40%, ~33% and ~20%, respectively). V'O2peak during CE was higher in RTA vs. CTRL (4.050.64 L min-1 vs. 3.560.30); no difference between groups was observed during KE. The O2 cost of CE exercise was not different between groups. When divided per muscle mass (for CE) or quadriceps muscle mass (for KE) V'O2peak was lower (by 15-20%) in RTA vs. CTRL. Vastus lateralis fractional O2 extraction was lower in RTA vs. CTRL at all work rates, both during CE and KE. RTA had higher ADP-stimulated mitochondrial respiration (56.723.7 pmolO2s-1mg-1 ww) vs. CTRL (35.710.2), and a tighter coupling of oxidative phosphorylation. In RTA the greater muscle mass and maximal force, and the enhanced mitochondrial respiration seem to compensate for the hypertrophy-induced impaired peripheral O2 diffusion. The net results are an enhanced whole body oxidative function at peak exercise, and unchanged efficiency and O2 cost at submaximal exercise, despite a much greater body mass Keywords: skeletal muscle, hypertrophy, mitochondrial respiration, oxidative metabolism, exercise Published in RUP: 15.10.2013; Views: 3997; Downloads: 151 Link to full text |
5. Functional impairment of skeletal muscle oxidative metabolism during knee-extension exercise after bed restDesy Salvadego, Stefano Lazzer, Mauro Marzorati, Simone Porcelli, Enrico Rejc, Boštjan Šimunič, Rado Pišot, Pietro Enrico Di Prampero, Bruno Grassi, 2011, original scientific article Keywords: microgravity, muscle atrophy, physical deconditioning, exercise tolerance, near-infared spectroscopy, skeletal muscle, bed rest Published in RUP: 15.10.2013; Views: 3894; Downloads: 215 Link to full text |