20.500.12556/RUP-21538 Red deer resequencing reveals the importance of sex chromosomes for reconstructing Late Quaternary events Sex chromosomes differ in their inheritance properties from autosomes, and hence may encode complementary information about past demographic events. We compiled and analysed a range-wide resequencing dataset of the red deer (Cervus elaphus), one of the few Eurasian herbivores of the Late Pleistocene megafauna still found throughout much of its historic range. Our analyses of 144 whole genomes reveal striking discrepancies between the population clusters suggested by autosomal and X-chromosomal data. We postulate that the genetic legacy of Late Glacial population structure is better captured and preserved by the X chromosome than by autosomes, for two reasons. First, X chromosomes have a lower Ne and hence lose genetic variation faster during isolation in glacial refugia, causing increased population differentiation. Second, following postglacial recolonisation and secondary contact, immigrant males pass on their X chromosomes to female offspring only, which effectively halves the migration rate when gene flow is male-mediated. Our study illustrates how a comparison between autosomal and sex chromosomal phylogeographic signals unravels past demographic processes which otherwise would remain hidden. red deer sex chromosome genomics navadni jelen spolni kromosom genomika true false false Angleški jezik Slovenski jezik Članek v reviji 2025-08-08 11:52:33 2025-08-08 11:52:39 2025-08-09 03:05:29 0000-00-00 00:00:00 2025 0 0 str. 1-17 iss. 2 Vol. 42 Feb. 2025 0000-00-00 NiDoloceno NiDoloceno NiDoloceno 0000-00-00 0000-00-00 2025-02-05 599.735.311:575.111 1537-1719 10.1093/molbev/msaf031 225588227 RAZ_Jong_Menno_J._de_2025.pdf RAZ_Jong_Menno_J._de_2025.pdf 1 510BA91F1B0626227E7ECDBB9B6A0558 aba0a43848f8761896276a51255a42efc6d62d5c2fdd4592b3cb58b91116514e 94cb62f6-743d-11f0-8f0b-005056ac49c0 https://repozitorij.upr.si/Dokument.php?lang=slv&id=31326 https://academic.oup.com/mbe/advance-article/doi/10.1093/molbev/msaf031/8002771 1 71d08525-743d-11f0-8f0b-005056ac49c0 https://repozitorij.upr.si/Dokument.php?lang=slv&id=31325 Fakulteta za matematiko, naravoslovje in informacijske tehnologije 0 0 0