20.500.12556/RUP-22515 From permits to samples addressing key challenges for high-quality reference genome generation in Europe High-quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample-handling procedures leading up to nucleic acid sequencing, covering tasks such as ensuring ethical and legal compliance, verifying accurate species identification, maintaining sample integrity during transport, and isolating high-quality DNA or nuclei. While many of the challenges and solutions we discuss are broadly relevant, our regulatory and logistical examples are primarily from Europe. By synthesising practical guidance, we highlight the crucial importance of taxonomic expertise, proper vouchering and biobanking, rigorous cold-chain management or alternative preservation methods, and emphasise adherence to packaging and shipping requirements for biological materials. We showcase examples spanning diverse regions, taxa and source materials, which underscore the importance of context-specific strategies and internationally harmonised protocols, particularly for metadata reporting. Our recommendations aim to support both small-scale projects and large initiatives, directing collective efforts to facilitate efficient sampling, vouchering and sample processing for future genomic studies. permits samples genomics dovoljenja vzorci genomika true false true Angleški jezik Slovenski jezik Članek v reviji 2026-01-21 11:01:12 2026-01-21 11:01:15 2026-01-22 03:05:44 0000-00-00 00:00:00 2026 0 0 str. 1-21 iss. 2, [article no.] e70100 Vol. 26 Feb. 2026 0000-00-00 Zaloznikova NiDoloceno NiDoloceno 0000-00-00 0000-00-00 2026-01-20 575.111 1755-0998 10.1111/1755-0998.70100 265540867 RAZ_Reichel_Katja_2026.pdf RAZ_Reichel_Katja_2026.pdf 1 4E22CCC43C29D55FBC19D15942E6E2A5 66a2569d1194b282bb4bc402f9e0075f6b8ea7786edfd4dc640c21552c859fe5 44d75779-f6b0-11f0-b092-005056ac49c0 https://repozitorij.upr.si/Dokument.php?lang=slv&id=32749 https://onlinelibrary.wiley.com/doi/10.1111/1755-0998.70100 1 21117b8f-f6b0-11f0-b092-005056ac49c0 https://repozitorij.upr.si/Dokument.php?lang=slv&id=32748 Fakulteta za matematiko, naravoslovje in informacijske tehnologije 0 0 0