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1.
Engaging European local communities in biodiversity genomics research : a five-step framework for scientists
Christian de Guttry, Chiara Bortoluzzi, Luísa S. Marins, Tinatin Chkhartishvili, Camilla R. De Pierri, Stefaniya Kamenova, Jennifer A. Leonard, Kay Lucek, Lada Lukić-Bilela, Camila J. Mazzoni, Elena Bužan, 2026, izvirni znanstveni članek

Opis: Biodiversity genomics research can inform conservation, management, and policy, including implementation and monitoring linked to the Kunming–Montreal Global Biodiversity Framework (KMGBF). Still, its societal relevance depends on how research is designed and interpreted with the people who live in, work with, and care for the species and places being studied. Local Communities often hold Local Ecological Knowledge that can improve sampling design, contextualise genomic patterns, and support the translation of findings into practice. Yet, community participation in biodiversity genomics remains limited, partly because researchers may lack practical guidance, training, incentives, or time for engagement. Here, we propose a five-step framework for engaging European Local Communities in biodiversity genomics projects. The framework covers early relationship building, respect for local context and knowledge, co-creation of research roles, transparent benefit sharing, and long-term knowledge transfer. We also outline biodiversity genomics-specific points that require early discussion, including biological sampling, genomic sequence data, genetic variant data, analytical outputs, associated ecological and locality information, Digital Sequence Information, repository deposition, interpretation, and reuse. The framework is intended as a practical starting point for research teams, funders, and community collaborators seeking to make biodiversity genomics research more transparent, locally informed, and useful for conservation decision-making.
Ključne besede: biodiversity conservation, community engagement, equitable research, knowledge co-creation, local ecological knowledge, participatory genomics
Objavljeno v RUP: 14.07.2026; Ogledov: 585; Prenosov: 25
.pdf Celotno besedilo (2,94 MB)
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2.
From permits to samples : addressing key challenges for high-quality reference genome generation in Europe
Katja Reichel, Jaakko Pohjoismäki, Jonas J. Astrin, Astrid Böhne, Chiara Bortoluzzi, Elena Bužan, Javier del Campo, Claudio Ciofi, Camilla B. Di-Nizo, Pradeep K. Divakar, 2026, pregledni znanstveni članek

Opis: High-quality reference genome assemblies have become essential for deepening our understanding of biodiversity, yet obtaining them for many species remains surprisingly challenging. Drawing on experiences from the European Reference Genome Atlas (ERGA) community, we focus on permit and sample-handling procedures leading up to nucleic acid sequencing, covering tasks such as ensuring ethical and legal compliance, verifying accurate species identification, maintaining sample integrity during transport, and isolating high-quality DNA or nuclei. While many of the challenges and solutions we discuss are broadly relevant, our regulatory and logistical examples are primarily from Europe. By synthesising practical guidance, we highlight the crucial importance of taxonomic expertise, proper vouchering and biobanking, rigorous cold-chain management or alternative preservation methods, and emphasise adherence to packaging and shipping requirements for biological materials. We showcase examples spanning diverse regions, taxa and source materials, which underscore the importance of context-specific strategies and internationally harmonised protocols, particularly for metadata reporting. Our recommendations aim to support both small-scale projects and large initiatives, directing collective efforts to facilitate efficient sampling, vouchering and sample processing for future genomic studies.
Ključne besede: permits, samples, genomics
Objavljeno v RUP: 21.01.2026; Ogledov: 994; Prenosov: 16
.pdf Celotno besedilo (1,22 MB)
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3.
Red deer resequencing reveals the importance of sex chromosomes for reconstructing Late Quaternary events
Menno J. de Jong, Gabriel Anaya, Aidin Niamir, Javier Pérez-González, Camilla Broggini, Alberto Membrillo del Pozo, Marcel Nebenfuehr, Eva de la Peña, Jordi Ruiz-Olmo, Jose Manuel Seoane, Elena Bužan, Laura Iacolina, 2025, izvirni znanstveni članek

Opis: Sex chromosomes differ in their inheritance properties from autosomes, and hence may encode complementary information about past demographic events. We compiled and analysed a range-wide resequencing dataset of the red deer (Cervus elaphus), one of the few Eurasian herbivores of the Late Pleistocene megafauna still found throughout much of its historic range. Our analyses of 144 whole genomes reveal striking discrepancies between the population clusters suggested by autosomal and X-chromosomal data. We postulate that the genetic legacy of Late Glacial population structure is better captured and preserved by the X chromosome than by autosomes, for two reasons. First, X chromosomes have a lower Ne and hence lose genetic variation faster during isolation in glacial refugia, causing increased population differentiation. Second, following postglacial recolonisation and secondary contact, immigrant males pass on their X chromosomes to female offspring only, which effectively halves the migration rate when gene flow is male-mediated. Our study illustrates how a comparison between autosomal and sex chromosomal phylogeographic signals unravels past demographic processes which otherwise would remain hidden.
Ključne besede: red deer, sex chromosome, genomics
Objavljeno v RUP: 08.08.2025; Ogledov: 1213; Prenosov: 55
.pdf Celotno besedilo (8,27 MB)
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