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Opis: Introduction The global increase in the older adult population has amplified interest in supporting aging in place. Age-related physical and cognitive limitations pose significant challenges, for example managing daily tasks such as medication or household activities can become increasingly difficult. This also burdens informal caregivers with emotional stress, time demands and care coordination. Assistive technologies can enhance autonomy, social connection and health management, but their long-term adoption and use remain limited. Methods Within the Pharaon project, the study explored factors influencing technology use among older adults after 12 months of use. The research focused on the Italian pilot while integrating insights from other European sites. Qualitative data from semi-structured interviews were analyzed thematically and validated through reflection meetings and iterative online questionnaires. Recurring factors were consolidated, prioritized and mapped to explore interconnections affecting adoption. Results Initial findings revealed 30 factors, including personal characteristics, motivational aspects, technical design, social dynamics, and environmental context. These were rated by participating teams and 25 were retained for deeper analysis. An interconnection analysis explored how these factors influenced one another. Highly interconnected factors, such as social context, personalized training, ease of use, and cognitive changes, were central to understanding and improving technology adoption. In contrast, aspects like education level, internet access, and technical requirements appeared less interconnected, indicating more isolated effects. Discussion This multi-site, empirical investigation emphasizes the complex and interconnected nature of technology adoption among older adults. Our findings underscore the need for user-centered design, tailored training, and sensitivity to social context. Furthermore, the interactive mapping of interrelated factors provides a practical framework for developers and policymakers to target impactful interventions. To our knowledge, this is the first cross-pilot study to empirically define and score factors affecting older adults’ technology use based on multi-pilot data across Europe, offering valuable insights for long-term, meaningful engagement.
Ključne besede: older adults, technology usage, factors influencing technology use, user experience, assistive technology
Objavljeno v RUP: 05.02.2026; Ogledov: 205; Prenosov: 3
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Opis: In this study, we examined the effects of information and communications technology (ICT) and financial development on mitigating gender inequality in Brazil, using autoregressive distributed lag (ARDL) approaches, between 1991 and 2022. The ARDL bounds test was employed to find the presence of co-integration within the series of data. Both in the short run and the long run, financial development has a significant negative impact on gender disparity; this means that policies aimed at enhancing women’s financial and consumption services should be promoted in the short run. In the long run, we can conclude that ICT developments lead to a decreasein gender inequalities, which may imply the need for strategic, long-term planning to increase ICT infrastructure, especially in deprived areas. This includes subsidising affordable internet, skills training for women in the ICT field, and promoting women’s participation in the technology industry. In addition, the impact of optimal financial development varies over time; hence, there is a need for flexibility and sustainability in financial development. Policy makers should therefore continue to strengthen and enhance financial inclusion initiatives, as well as regularly follow up on the impact of these initiatives on gender equality.
Ključne besede: gender inequality, information and communications technology, financial development, human capital index, agriculture
Objavljeno v RUP: 16.01.2026; Ogledov: 171; Prenosov: 0
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Opis: The digital environment is different from natural and social environments. Technologies are evolving to support new methods of collaborative learning and interaction. A key challenge is to ensure that technology-enhanced education is effective and creates a supportive environment for students. This requires considering adaptive motivations, emotions, and psychological factors such as intrinsic motivation, cognitive load and self-regulation, all which influence student engagement and success in digital learning. This chapter provides an overview of literature on psychological processes important in digital learning. Factors such as motivation, cognitive management, and self-regulation shape student performance in these environments. The psychology of digital learning explores the cognitive, emotional, and social dimensions of education in the digital age. Research aims to optimize these environments for better learning outcomes. Understanding these psychological elements is essential for educators to create more effective, engaging, and enjoyable digital learning experiences, though the field is still developing, and many aspects remain to be explored.
Ključne besede: digital learning, intrinsic motivation, cognitive load, self-regulation, technology-enhanced education
Objavljeno v RUP: 19.12.2025; Ogledov: 208; Prenosov: 3
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Opis: Our study introduces a novel bacteriophage-based vaccine strategy and evaluates its antitumor efficacy, both as a standalone therapy and in combination with gene electrotransfer (GET) of interleukin-12 (IL-12) plasmids. Using phage display technology, we produced engineered M13 bacteriophages expressing tumour peptides MAGE-A1, gp100, or MART-1/MELAN-A on the surface of the capsid. The therapeutic potential of bacteriophage vaccination alone or in combination with GET IL-12 was tested in vivo in a mouse malignant melanoma model. Response to treatment was further characterized by histological and immunohistochemical analyses of tumour tissue. No negative side effects were observed during treatment in mice. Engineered bacteriophage therapy significantly delayed tumour growth. GET IL-12 contributed to the therapeutic effect of engineered bacteriophages and increased tumour growth delay. Both therapies had a synergistic effect and led to complete responses in 30% of cases. Histological and immunohistochemical analyses have shown that both bacteriophage monotherapy and, especially in combination with GET IL-12, activate the immune system and increase the proportion of necrosis and the infiltration of macrophages, CD4 + and CD8 + T lymphocytes in tumours. For the first time, a cocktail of three engineered M13 bacteriophages displaying different melanoma-associated antigens with intratumoral IL-12 gene electrotransfer were applied, demonstrating a synergistic therapeutic effect in a highly aggressive melanoma model. Nanotechnological approaches, such as the use of genetically engineered bacteriophages, offer promising new avenues for the development of anti-tumour vaccines.
Ključne besede: immunotherapy, bacteriophages, bacteriophage display technology, bacteriophage vaccine, interleukin, gene electrotransfer, malignant melanoma
Objavljeno v RUP: 16.06.2025; Ogledov: 966; Prenosov: 6
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Ključne besede: central bank digital currencies, distributed ledger technology, monetary and financial system, (nonbank) financial intermediation, digital euro, monetary policy
Objavljeno v RUP: 03.02.2025; Ogledov: 1555; Prenosov: 42
Celotno besedilo (1,91 MB)