11. Optimizacija oskrbe pacientov v onkološki zdravstveni negi na podlagi McGillovega sodelovalnega modelaValentina Masten, Tamara Milić, Matic Petrovič, Mirko Prosen, Sabina Ličen, 2025, izvirni znanstveni članek Opis: Izhodišča: McGillov model zdravstvene nege je celostni, sodelovalni pristop, ki poudarja aktivno vlogo pacienta, vključevanje bližnjih in krepitev psihosocialne podpore. Kljub uveljavljenosti v mednarodnem prostoru njegova uporaba v slovenski klinični praksi še ni bila raziskana. Namen raziskave je bil ovrednotiti, v kolikšni meri medicinske sestre na področju onkološke zdravstvene nege uporabljajo pristope McGillovega modela, ki vključujejo sodelovanje pacientov, vključevanje družinskih članov in krepitev psihosocialne podpore. Metode: V kvantitativni presečni raziskavi je bilo k sodelovanju povabljenih približno 400 medicinskih sester, zaposlenih na področju onkološke zdravstvene nege. Vprašalnik je pričelo izpolnjevati 166 oseb, od tega ga je popolnoma izpolnilo 126 (odzivnost 31,5 % glede na populacijo medicinskih sester zaposlenih na področju onkološke zdravstvene nege). Večina anketirancev je bila ženskega spola (77,8 %). Povprečna starost anketirancev je bila 37,71 leta (s = 8,07) s povprečno delovno dobo na področju onkološke zdravstvene nege 9,66 leta (s = 7,93). Analiza je temeljila le na popolnoma rešenih vprašalnikih. Podatke smo zbrali z novo razvito lestvico, ki temelji na McGillovem sodelovalnem modelu. Anketiranci so trditve ocenjevali na petstopenjski lestvici, ki meri pogostost izvajanja pristopov ali stopnjo strinjanja z izjavo. Izvedli smo eksploratorno in konfirmatorno faktorsko analizo, Wilcoxonove in Mann–Whitneyjeve teste ter Spearmanovo korelacijo. Rezultati: Faktorska analiza je potrdila tri konstrukte, ki pojasnjujejo 65,3 % skupne variance (KMO = 0,896; Bartlett p < 0,001). Empirične mediane vseh treh konstruktov so bile statistično značilno višje od teoretičnih (p < 0,001), kar pomeni, da so anketiranci poročali o uporabi pristopov McGillovega modela. Anketiranci z dostopom do pisnih protokolov ali organizacijsko podporo so dosegali višje rezultate (p < 0,001). Ugotovljene so bile zmerne do visoke pozitivne korelacije med uporabo pristopov in zaznavo izboljšanja oskrbe ter psihosocialnega stanja onkoloških pacientov (p < 0,001). Zaključek: Rezultati potrjujejo, da se v onkološki zdravstveni negi pogosto uporabljajo pristopi McGillovega modela, kar pozitivno sovpada z zaznanim izboljšanjem kakovosti oskrbe. Model ima potencial za širšo in bolj formalizirano implementacijo v klinično prakso. Ključne besede: McGillov model zdravstvene nege, medicinske sestre, onkološka zdravstvena nega, psihosocialna podpora, sodelovanje pacienta Objavljeno v RUP: 29.12.2025; Ogledov: 237; Prenosov: 8
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12. An analysis of nurse prescribing in Slovenia and Croatia : current practices, attitudes, and future perspectivesMarko Petrović, Benjamin Osmančević, Sabina Ličen, Mirko Prosen, 2025, izvirni znanstveni članek Ključne besede: zdravstvena njega, farmakologija, zdravila, predpisovanje zdravil, medicinske sestre, Slovenija, Hrvaška Objavljeno v RUP: 29.12.2025; Ogledov: 293; Prenosov: 1
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13. Dynamic strength index in athletic performance : a comprehensive analysis of theory, measurement and practical applicationMarko Joksimović, Ratko Pavlović, Vladimir Koprivica, Matej Plevnik, 2025, izvirni znanstveni članek Opis: Background and purposeThe development of athletic performance requires a detailed assessment of the relationship between maximal strength and the ability to express it explosively. Traditional tests one-repetition maximum do not differentiate the rate of force development, which led to the introduction of the Dynamic Strength Index, defined as the ratio between force in the countermovement jump and the isometric mid-thigh pull . The aim of this paper was to present the theoretical background, methodological approaches, and practical applications of Dynamic Strength Index in order to optimize training and prevent injuries.Materials and methodsDynamic Strength Index is calculated by measuring peak force in countermovement jump and isometric mid-thigh pull tests using a force plate. Standardization of protocols (body position, contraction duration, software processing) is essential for validity. Test–retest reliability is high (Intraclass Correlation Coefficient >0.90). Normative values vary by sport and playing position: for example, sprinters and jumpers often record Dynamic Strength Index values >0.80, while weightlifters usually show lower values (<0.60).ResultsFindings indicate that DSI is an effective tool for training individualization. Values below 0.60 suggest the need for plyometric and ballistic training, while values above 0.80 point to a focus on maximal strength development. The optimal range (0.60–0.80) reflects a balanced profile. DSI is also useful for longitudinal monitoring of adaptations, adjusting training loads, and identifying injury risks. However, variability in testing protocols, anthropometric differences, and software processing may limit its applicability and comparability across studies.ConclusionDynamic Strength Index is a valuable biomechanical indicator linking maximal and explosive strength, allowing precise programming of training and performance monitoring. Its use has already been established in elite sports, but full validation requires measurement standardization and the development of sport-specific normative databases. Future directions include phase-specific force analysis within contraction cycles, expanding testing protocols, and integrating digital platforms for automated analysis. Ključne besede: strength, index, performance Objavljeno v RUP: 28.12.2025; Ogledov: 231; Prenosov: 3
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14. First EST-SSRs of Helichrysum italicum (Roth) G. Don (Asteraceae) revealed insights into the genetic diversity and population structure in CorsicaPetra Gabrovšek, Matjaž Hladnik, Dunja Bandelj, Zala Jenko Pražnikar, Saša Kenig, Félix Tomi, Marc Gibernau, Slavko Brana, Alenka Baruca Arbeiter, 2025, izvirni znanstveni članek Opis: Helichrysum italicum (Roth) G. Don (Asteraceae) is a valuable medicinal and aromatic plant native to a variety of habitats across the Mediterranean region. However, genetic studies of this morphologically diverse species have been limited by the scarcity of species-specific DNA markers. To address this limitation, we generated the first de novo transcriptome assembly comprising 24,806 transcripts from young shoots containing leaves and flowers, developed EST-SSR markers, and evaluated their utility in population genetic analysis. Seventy-eight primer pairs were designed, of which 23 showed successful amplification, polymorphism, and transferability to Helichrysum litoreum Guss. and Helichrysum arenarium (L.) Moench. A subset of 12 EST-SSRs was used to genotype 270 individuals from 12 natural populations of H. italicum in Corsica (France), along with one outgroup population from Croatia. The polymorphic information content ranged from 0.250 to 0.796, and Shannon’s information index ranged from 0.588 to 1.843, indicating the markers’ suitability for popu- lation genetic studies. Analysis of molecular variance revealed that 15% of the total genetic variation was attributable to differences among populations. Discriminant analysis of principal components and Bayesian clustering in STRUCTURE identified distinct popu- lation clusters corresponding to geographic locations. Notably, the southernmost coastal populations were clearly differentiated from the others. Ključne besede: Helichrysum italicum, immortelle, de novo transcriptome, genic microsatellite markers, EST-SSRs, population study, Corsica, Mediterranean Basin Objavljeno v RUP: 17.12.2025; Ogledov: 261; Prenosov: 7
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15. Polyphenolic composition, genetic profile and in vitro antioxidant and cytotoxic activities of artichoke varieties “Strunjanska articoka”, “Romanesco” and "Violetto di Romagna"Katja Kramberger, Alenka Baruca Arbeiter, Ana Petelin, Petra Gabrovšek, Nemanja Teslić, Saša Kenig, Aleksandra Mišan, Dunja Bandelj, Alena Stupar, Zala Jenko Pražnikar, 2025, izvirni znanstveni članek Opis: In recent years, artichokes have gained attention as functional foods due to their polyphenol content and health benefits. While Italian varieties have been widely studied, the Slovenian landrace “Strunjanska articoka” remains largely unexplored. This study compared “Strunjanska articoka” with two Italian varieties, “Romanesco” and “Violetto di Romagna”, assessing genetic profiles, chemical composition, antioxidant activity, and effects on lipid accumulation. The genetic analysis confirmed the uniqueness and clear differentiation of the landrace “Strunjanska articoka” from the two commercial varieties. Analysing the profiles of phenolic compounds in the leaf extracts of these morphologically different artichoke varieties underlines their unique phytochemical composition, which translates into different health benefits. “Romanesco” showed the highest free radical scavenging activity (EC50 = 100 µg/mL), followed by “Strunjanska articoka” (EC50 = 143 µg/mL), and “Violetto di Romagna” (EC50 = 160 µg/mL). Importantly, “Strunjanska articoka” demonstrated superior cytoprotective effects against oxidative stress in HepG2 and CCD112CoN cells. It also reduced lipid accumulation in HepG2 cells, along with “Violetto di Romagna,” whereas “Romanesco” did not. These findings justify further investigation into the potential therapeutic effects of “Strunjanska articoka” and support the rationale for its cultivation. Ključne besede: artichoke leaf extracts, phenolic compounds, antioxidative potential, lipid accumulation Objavljeno v RUP: 06.12.2025; Ogledov: 311; Prenosov: 4
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16. The effect of gamification-based exercises on footA systematic review and meta-analysis : a posture in children and adolescents with flatfoot:Ebrahim Ebrahimi, Rahman Sheikhhoseini, Žiga Kozinc, Seyed Alihossein Nourbakhsh, 2025, pregledni znanstveni članek Opis: BackgroundGamification has emerged as a novel approach in rehabilitation. This systematic review and meta-analysis aimed to evaluate the effectiveness of gamification-based exercises on foot posture in children and adolescents with flatfoot. MethodsA systematic review and meta-analysis were conducted in accordance with PRISMA guidelines, utilizing the PubMed, Scopus, Web of Science, and Google Scholar databases to search for original and peer-reviewed articles with selected keywords from inception to July 2025. The quality of the included studies was assessed using the Joanna Briggs Institute checklist. Statistical analysis was conducted with Comprehensive Meta-Analysis software version 3. To evaluate data heterogeneity, the Q-test and I2 statistic were applied. Egger’s test was used to assess publication bias. ResultsAfter searching the mentioned databases, 2160 articles were found. Finally, seven articles were included in the current review. It was shown that gamification-based exercise had a significant effect, leading to a reduction in navicular drop (95% CI = −1.796 to −0.516, p = 0.000) and an increase in balance scores (95% CI = −1.647 to −0.462, p = 0.000), compared to the passive control groups that did not receive any intervention. However, no significant differences were seen in the Staheli index (95% CI = −3.298 to 0.023, p = 0.053). High heterogeneity was noted in the navicular drop test (95% CI = −2.412 to −0.603, p = 0.001). Egger’s test indicated no statistically significant publication bias for either navicular drop (p = 0.080) or Staheli index (p = 0.210). ConclusionThe results showed that exercise with gamification may be effective in improving foot alignment in children and adolescents. Specifically, positive effects were evident when using the navicular drop test, whereas no significant changes were detected with the Staheli index. However, interpretation should be made cautiously due to the limited number of studies and lack of age or gender stratification. Ključne besede: flatfoot, gamification, therapeutic exercise, meta-analysis Objavljeno v RUP: 04.12.2025; Ogledov: 297; Prenosov: 8
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17. Redox state is similar in subjects following omnivorous, vegan, vegetarian, and low-carbohydrate high-fat dietNives Bogataj Jontez, Karin Šik Novak, Zala Jenko Pražnikar, Ana Petelin, Nina Mohorko, Saša Kenig, 2025, izvirni znanstveni članek Opis: Age-related noncommunicable diseases are a major health burden in developed countries, with oxidative stress being a key contributing factor. This cross-sectional study aimed to test the hypothesis that redox status among 88 participants with a particular interest in nutrition and habitually following 4 popular dietary patterns (vegan, vegetarian, low-carbohydrate high-fat, and omnivorous), is similar, but correlates with diet quality. Dietary intake was assessed using food diaries, and venous blood samples were collected to measure serum total antioxidative capacity (TAC), bilirubin, nicotinamide adenine dinucleotide (NAD⁺)/reduced form of nicotinamide adenine dinucleotide (NADH) ratio, and sirtuin 1 concentration, and the expression of antioxidative enzymes in leukocytes. TAC and the NAD⁺/NADH ratio were higher in the vegan group compared with the vegetarian group, whereas bilirubin concentration was higher in the omnivorous compared with the low-carbohydrate high-fat group. Other differences between the dietary groups were not significant. NAD+/NADH ratio and sirtuin 1 were positively correlated with diet quality, assessed with the Healthy Eating Index. Correlation analysis between dietary variables and redox markers revealed only a few weak to moderate associations. However, a hierarchical regression model including age, gender, and dietary variables explained 19.8% of the variance in TAC, 21.2% of the variance in the NAD⁺/NADH ratio, and 44.3% of the variance in sirtuin 1 concentration. Therefore, in healthy, relatively young participants with appropriate energy intakes, endogenous mechanisms are able to compensate for oxidative stress to a similar extent, regardless of dietary pattern. Nonetheless, overall diet quality and food selection appear to play a meaningful role in redox balance. Ključne besede: oxidative stress, total antioxidative capacity, sirtuin 1, diet quality Objavljeno v RUP: 02.12.2025; Ogledov: 341; Prenosov: 2
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18. Joint torque and electromyographic activity during eccentric exercise for hip adductors at different hip flexion anglesJan Marušič, Oskar Cvjetičanin, Nejc Šarabon, 2025, izvirni znanstveni članek Opis: Our objective was to investigate the effects of three hip flexion angles (0°, 45°, and 90°) and leg dominance on peak joint torque, angle at peak torque, and peak electromyographic activity (EMGA) of the adductor longus during bilateral eccentric hip adduction. Sixteen recreationally active participants completed bilateral eccentric contractions at each hip flexion angle using a custom-built dynamometer. The primary outcome measures were peak adduction torque, angle at peak torque, and EMGA of the adductor longus. A 3×2 repeated measures ANOVA was used to assess the effects of hip angle and leg dominance. Hip flexion angle had a significant main effect on peak torque (F(2, 30) = 15.75, p<0.01), with peak torque significantly lower at 90° compared to 0° and 45°. No significant effects were observed for leg dominance or interaction. No significant main effects of hip flexion angle, leg dominance, or their interaction were observed on peak EMGA or peak torque angle. Eccentric hip adduction strength is reduced at 90° of flexion, likely due to mechanical disadvantage, while neural activation remains unchanged. These findings support the use of less flexed positions in eccentric training protocols for adductor strength development or injury prevention. Ključne besede: adductor longus, eccentric training, injury prevention, strength Objavljeno v RUP: 19.11.2025; Ogledov: 395; Prenosov: 9
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19. The usefulness of a body shape index in assessing muscle function and strength in older adults hemodialysis patients : aBojan Knap, Boštjan Žvanut, Lucija Brezočnik, Mihaela Jurdana, 2025, izvirni znanstveni članek Opis: Objective: This study investigates the relationship between a new anthropometric measure, the Body Shape Index (ABSI), and body composition and biochemical parameters in hemodialysis patients and, for the first time, the correlation between ABSI and muscle strength and function in these patients. Methods: A cross-sectional study was conducted on a sample of 80 patients who were regularly treated in the hemodialysis unit of a single medical center of the University Hospital of Ljubljana, Slovenia. General anthropometric parameters body mass index (BMI) and ABSI=(WC/(BMI2/3x height½) as well as body composition data (fat mass FM, fat-free mass FFM, fat-free mass index FFMI, skeletal muscle index SMI) were determined in 25 women (aged 74.5 ± 7.5 years) and 55 men (aged 70.1 ± 6.6 years) with overweight (25 kg/m2 ≤ BMI < 30 kg/m2) and obesity (BMI ≥ 30 kg/m2) by bioelectrical impedance analysis (BIA). Muscle strength was determined using a hand grip strength test, while muscle performance was assessed using the sit-to-stand test. Results: ABSI was significantly negatively associated with muscle strength, functional tests and SMI only in men. Based on the median ABSI value (0.090273 m11/6·kg−2/3 in women and 0.090893 m11/6·kg−2/3 in men), women with a higher ABSI had a significantly higher glucose concentration than those with a lower ABSI. Men with a lower ABSI obtained significantly better results in the hand grip test, sit-to-stand test and waist circumference (WC). In conclusion, our findings suggest an inverse association between ABSI and muscle strength and function in male hemodialysis patients, indicating that higher ABSI may reflect poorer physical condition in this population. Further longitudinal studies are needed to explore the clinical significance of this relationship. Ključne besede: hemodialysis, muscle strenght, sarcopenia Objavljeno v RUP: 10.11.2025; Ogledov: 389; Prenosov: 7
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20. Eccentric quasi-isometric exercise produces greater impulse with less pain than isokinetic heavy–slow resistance exercise in ankle plantar flexors : quasi-randomized controlled trialLuka Križaj, Žiga Kozinc, Nejc Šarabon, 2025, izvirni znanstveni članek Opis: Recently, there has been growing interest in optimizing exercise protocols in sports training and rehabilitation, with particular attention to eccentric quasi-isometric (EQI) contractions, which involve maintaining joint position until isometric failure and then resisting the subsequent eccentric phase. Evidence directly comparing EQI with other contraction modes remains scarce. This quasi-randomized controlled trial examined the short-term effects of EQI versus isokinetic heavy–slow resistance (IHSR) exercises on ankle plantar flexors, focusing on pain, range of motion (RoM), and strength performance. Thirty-two physically active participants were allocated to EQI (n = 16) or IHSR (n = 16) groups and assessed at baseline, immediately post-exercise, and 24 and 48 h later. Both groups performed three exercise sets with 3 min breaks. The protocols were designed to approximate matched loading, based on preliminary testing. Nevertheless, the EQI group achieved a significantly greater total impulse (p = 0.028), a shorter time under tension (p = 0.001), and lower effort scores (p < 0.001). Group × time analysis revealed less decline in maximal voluntary isometric contraction torque (p = 0.002; η2 = 0.16), as well as lower general (p < 0.001; η2 = 0.32) and activity-related pain (p < 0.001; η2 = 0.32) in the EQI group, with no significant differences in dorsiflexion RoM (p = 0.893). In conclusion, EQI produced a higher torque impulse while inducing less fatigue and post-exercise pain than IHSR, suggesting it may be a more efficient loading strategy for the ankle plantar flexors. The results contribute to the understanding of contraction-specific efficiency, and may inform the design of future training and rehabilitation protocols targeting the ankle plantar flexors. Ključne besede: eccentric quasi-isometric contraction, isokinetic heavy–slow resistance contraction, ankle plantar flexors, impulse, pain, range of motion Objavljeno v RUP: 27.10.2025; Ogledov: 418; Prenosov: 10
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