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11.
Occupational and non-occupational device-measured movement behaviours and low back pain : a compositional isotemporal substitution analysis
Kaja Kastelic, Nejc Šarabon, Michael David Burnard, Željko Pedišić, 2026, izvirni znanstveni članek

Opis: Background: Physical activity, sedentary behaviour, and sleep were shown to be independently associated with low back pain (LBP). The aim of this cross-sectional study was to explore the associations between 24-hour movement behaviour compositions and the occurrence, severity, and estimated level of LBP impact on an individual’s life. Methods: A convenience sample of 197 adults (40% females, 37 ± 11 years of age) were asked to wear an activPAL accelerometer for at least 7 consecutive days to assess their time-use composition consisting of moderate- to vigorous-intensity physical activity (MVPA), light- intensity physical activity (LPA), sedentary behaviour (SB), and sleep and to complete a questionnaire on LBP and sociodemographic characteristics. Compositional isotemporal substitution analyses were conducted separately for the non-domain-specific and domain- specific (including occupational and non-occupational domains) movement behaviour compositions. Results: Reallocating time from MVPA to any other movement behaviour or from sleep to LPA was associated with a higher LBP impact score. For example, reallocating 60 min/day from MVPA to LPA was associated with on average 17 points (95% CI: 6 to 28) higher LBP impact score (on a 0-70 scale). We did not find significant associations between the domain- specific time-use composition and LBP impact score (p = 0.060). We also did not find significant associations of the time-use compositions with occurrence and severity of LBP (p- value range: 0.067 to 0.649). Conclusion: Our study suggests that LBP sufferers with higher MVPA and sleep better cope with LBP. The differences in the LBP impact scores associated with theoretical reallocations between movement behaviours may be deemed clinically important. Future longitudinal and experimental studies in population-representative samples are needed to confirm our findings.
Ključne besede: musculoskeletal health, physical behaviours, time-use epidemiology
Objavljeno v RUP: 30.03.2026; Ogledov: 351; Prenosov: 8
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12.
Targeting skeletal muscle melatonin-MT2 signaling to attenuate the obesity-cancer axis : a metabolic perspective
Mihaela Jurdana, Lovro Žiberna, 2026, pregledni znanstveni članek

Opis: Obesity and metabolic syndrome promote malignancies through chronic inflammation and sustained activation of insulin and insulin-like growth factor-1 (IGF-1) signaling. Skeletal muscle is central to this tumor-promoting milieu because it governs insulin-stimulated glucose disposal, lipid oxidation, and endocrine crosstalk. This narrative review explores whether melatonin signaling in skeletal muscle, particularly via melatonin receptor 2 (MT2), represents a modifiable node within the obesity–cancer axis. Experimental evidence indicates that melatonin activates MT2-linked Gi/o and calcium-sensitive pathways converging on phosphoinositide 3-kinase–protein kinase B (PI3K–Akt), extracellular signal-regulated kinases (ERK), and calcium/calmodulin-dependent protein kinase II–adenosine monophosphate-activated protein kinase–peroxisome proliferator-activated receptor gamma coactivator 1-alpha (CaMKII–AMPK–PGC-1α) signaling. These pathways enhance insulin sensitivity, mitochondrial function, and lipid partitioning while reducing myosteatosis and cellular stress. By improving muscle quality, melatonin may lower systemic insulin and IGF-1 drive and inflammatory adipokine tone that fuel tumor-promoting PI3K–Akt–mammalian target of rapamycin (mTOR) signaling. However, human evidence remains limited and timing-dependent. Melatonin exposure in the fed state or near carbohydrate intake may worsen glycemia, particularly in carriers of melatonin receptor 1B (MTNR1B) risk alleles. Chronobiology-informed, genotype-guided trials with detailed muscle phenotyping and cancer-relevant endpoints are warranted.
Ključne besede: melatonin, melatonin receptor 1, melatonin receptor 2, melatonin receptor 1A gene, melatonin receptor 1B gene, skeletal muscle, insulin resistance, myosteatosis, sarcopenic obesity, myokines, obesity-related cancer
Objavljeno v RUP: 26.03.2026; Ogledov: 346; Prenosov: 22
.pdf Celotno besedilo (1,56 MB)
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13.
Effects of foot strengthening exercises with or without a toe spacer on hallux alignment, foot mobility, and balance : a randomized controlled trial
Sara Gloria Meh, Miha Pešič, Žiga Kozinc, 2026, izvirni znanstveni članek

Opis: Background: Intrinsic foot muscle strengthening and orthotic devices such as toe spacers are commonly used to improve foot alignment and function. However, evidence regarding the combined effects of strengthening exercises and interdigital spacers remains limited. Objective: To examine whether adding a silicone toe spacer to a foot strengthening exercise program provides additional benefits compared with exercise alone. Design: Randomized controlled trial. Setting: University biomechanics laboratory. Participants: Twenty-five healthy adults (mean age 23.8 ± 1.3 years) without lower limb injury or neurological disorders were randomly allocated to one of two intervention groups. Interventions: Participants performed a six-week foot strengthening program (22 sessions). One group performed exercises alone, while the second group performed the same exercises while wearing a silicone interdigital toe spacer. Main outcome measures: The primary outcome was hallux valgus angle. Secondary outcomes included active and passive hallux range of motion (ROM), ankle dorsiflexion ROM (weight-bearing lunge test), navicular drop, and postural stability during single-leg stance assessed using center-of-pressure (CoP) measures. Results: Both groups demonstrated improvements over time in hallux valgus angle (p = 0.001, η2 = 0.361), active hallux range of motion (p < 0.001, η2 = 0.545), and ankle dorsiflexion (p < 0.001). However, no significant between-group differences were observed for the primary outcome or most secondary outcomes. A significant time × group interaction was observed only for passive hallux range of motion (p = 0.040, η2 = 0.170), indicating greater improvement in the exercise-only group. Navicular drop and postural stability variables did not change significantly. Conclusions: A six-week foot strengthening program improved hallux alignment, hallux mobility, and ankle dorsiflexion in healthy adults. The addition of a silicone toe spacer did not provide additional short-term benefits compared with exercise alone.
Ključne besede: foot, orthosis, thumb
Objavljeno v RUP: 26.03.2026; Ogledov: 485; Prenosov: 10
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14.
Start detection in resisted sprinting : a validity and reliability analysis of encoder- and sensor-based methods
Oskar Cvjetičanin, Matic Sašek, Živa Mesec, Nejc Šarabon, 2026, izvirni znanstveni članek

Opis: This study evaluated the validity and reliability of start detection methods for determining 5-m sprint time using a resistance device with an encoder. Seventeen recreationally trained participants completed 12 resisted 5-m sprints across two sessions. Sprint start was identified using three encoder-based methods (position, velocity [MEv], and acceleration), a rear-foot release sensor and hip-marker kinematics (KIN) as a proxy for forward center-of-mass displacement. Reliability was evaluated using intraclass correlation coefficient (ICC), coefficient of variation (CV), typical error (TE), standard error of measurement (SEM), and minimal detectable change (MDC), while agreement was examined using Pearson correlations and Bland-Altman analysis. All methods showed moderate to excellent reliability (ICC = 0.54–0.93; CV ≤ 11.1%) and strong agreement with KIN (r = 0.90–0.94). MEv showed the smallest bias (−0.00 ± 0.07 s) and narrowest 95% limits of agreement, and is therefore preferred for sprint start detection in practical settings.
Ključne besede: resisted sprinting, sprint start, encoder, performance monitorin
Objavljeno v RUP: 26.03.2026; Ogledov: 347; Prenosov: 14
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15.
Assessing muscle shear modulus with shear-wave elastography during neuromuscular fatigue : a review
Saša Maučec, Žiga Kozinc, 2026, pregledni znanstveni članek

Ključne besede: fatigue, elastograhy, ultrasound
Objavljeno v RUP: 22.03.2026; Ogledov: 425; Prenosov: 8
.pdf Celotno besedilo (702,79 KB)
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16.
Adherence and metabolic outcomes of early and late time-restricted eating with energy restriction vs. energy restriction alone : a 6-month follow-up
Tanja Črešnovar, Bernarda Habe, Nina Mohorko, Saša Kenig, Zala Jenko Pražnikar, Ana Petelin, 2026, izvirni znanstveni članek

Opis: Background/Objectives: Long-term weight maintenance remains challenging with conventional dietary strategies due to various barriers. Time-restricted eating (TRE) has recently attracted attention as a potential approach to improve adherence, but evidence on long-term maintenance is limited. We investigated the 6-month follow-up (6FU) of early time-restricted eating with energy restriction (eTRE + ER), late time-restricted eating with energy restriction (lTRE + ER) and energy restriction alone (ER). Methods: This 6FU included 69 of 93 participants from a previously conducted 3-month intervention (3INT). After the intervention, participants returned to free-living conditions without dietary guidance. Outcomes included adherence, perceived barriers, body composition, blood pressure, cardiometabolic risk factors, metabolic hormones, subjective appetite, and dietary intake. Results: Adherence of at least ≥5 days per week was low: 7.7% (eTRE + ER), 18.2% (lTRE + ER), and 9.5% (ER). Reduced adherence during the 6FU was associated with a partial reversal of improvements in body mass, body composition, cardiometabolic risk factors, metabolic hormones, and subjective appetite observed during the 3INT. Analysis of perceived barriers showed that environmental and psychosocial barriers were significant predictors of changes in body mass during the 6FU, while environmental and behavioral barriers were associated with extension of the eating window. These associations were most pronounced in the eTRE + ER group. Conclusions: During the 6FU, differences between dietary strategies gradually diminished, although some remained clinically meaningful. Long-term adherence was low across all three dietary strategies, with psychosocial, environmental, and behavioral barriers particularly evident in the eTRE + ER group. Further research is needed to confirm long-term adherence before TRE + ER interventions can be widely applied in clinical practice.
Ključne besede: early time-restricted eating, late time-restricted eating, energy restriction, overweight, obesity
Objavljeno v RUP: 22.03.2026; Ogledov: 499; Prenosov: 13
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17.
Machine learning identifies distinct movement control impairment clusters in patients with chronic neck pain
Živa Majcen Rošker, Jernej Rošker, 2026, izvirni znanstveni članek

Opis: atients with chronic neck pain experience various impairments, with reduced movement control suggested as a significant contributing factor. The heterogeneity of this patient population and suboptimal rehabilitation outcomes suggests the existence of latent subgroup characteristics. The aim of this study was to identify distinct groups among patients with neck pain based on the movement control test and pain intensity and to provide information on cluster-specific impairments. 135 patients with idiopathic neck pain performed a movement control test (the Butterfly test) at three difficulty levels and were assessed for pain intensity, providing 13 different parameters (classifiers). Louvain, hierarchical and k-means clustering methods were applied and the number of clusters determined by observing the symmetry and size of silhouette scores. Further, different machine learning algorithms were applied to develop and evaluate a classification framework (based on AUC, classification accuracy, sensitivity, and specificity) and to provide information on individual cluster characteristics using the Shapley Additive Explanations. The k-means and deep learning neural network methods provided the most efficient clustering and classification performance extracting 4 meaningful clusters. Patients between groups differed in the amount of impairment, with cluster 2 and 1 representing the most severe impairments and with clusters 3 and 4 the least severe impairments. Additionally, specific motor control impairments were observed in individual clusters suggesting distinct neck movement control adaptations. Identifying subgroups of patients with neck pain and their specific characteristics based on the results of the Butterfly test may inform future development of targeted rehabilitation strategies.
Ključne besede: neck pain, kinesthesia, proprioception clustering, machine learning
Objavljeno v RUP: 16.03.2026; Ogledov: 455; Prenosov: 6
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18.
Slovenian 24-Hour Movement Guidelines and adherence among older adults : preliminary findings from the National Health-Related Lifestyle Survey 2024
Tjaša Knific, Kaja Kastelic, Nejc Šarabon, 2025, objavljeni povzetek znanstvenega prispevka na konferenci

Ključne besede: time-use epidemiology, recommendations, healthy ageing, GIB24, CINDI
Objavljeno v RUP: 02.03.2026; Ogledov: 374; Prenosov: 11
.pdf Celotno besedilo (245,72 KB)
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19.
Comparison of vertical jump performance between the Maasai, track and field athletes, and non-athletes : a cross-sectional study
Petra Robnik, Jaffu Chilongola, Eunice Kombe, Žiga Kozinc, 2026, izvirni znanstveni članek

Opis: The Maasai are known for their unique customs, including dancing, singing, and jumping. The tribe’s traditional jumping rituals, performed by young warriors called ‘Morani,’ demonstrate their strength and skill through repetitive hops, often lasting several hours. These jumps are comparable to the countermovement jumps (CMJ) of elite Western athletes. This study compared different types of jumps (CMJ), squat jump (SJ) and repetitive hops) among three groups: (a) Maasai (n = 30), (b) Slovenian high-jump athletes and sprinters (n = 20), and (c) non-athletes in Slovenia (n = 20). Participants were male, aged 16–35. The My Jump 2 app was used to measure jump height. Results showed that during CMJ, the Maasai averaged 38.1 cm ± 7.3 cm; athletes 52.46 cm ± 9.07 cm; non-athletes 33.72 cm ± 7.22 cm. In the SJ, the Maasai averaged 35.87 cm ± 6.59 cm; athletes 49.74 cm ± 7.3 cm; non-athletes 32.57 cm ± 6.21 cm. For repetitive hops, the Maasai averaged 36.2 cm ± 7.75 cm; athletes 35.93 cm ± 5.98 cm; non-athletes 20.98 cm ± 7.07 cm. Athletes showed higher jump heights in CMJ and SJ compared to the Maasai (p < 0.001, d = 1.28; p < 0.001, d = 2.00) and non-athletes (p < 0.001, d = 2.29; p < 0.001, d = 2.53). However, in repetitive hops, the Maasai performed similarly to athletes (p = 0.991, d = 0.04), while non-athletes had significantly lower results (p < 0.001, d = 2.05). These findings suggest that the Maasai’s cultural practices enhance musculoskeletal adaptation from an early age, emphasizing that proficiency is greatest in regularly practiced tasks, such as repetitive jumps and hops.
Ključne besede: Maasai, athletes, jumps
Objavljeno v RUP: 01.03.2026; Ogledov: 604; Prenosov: 6
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20.
Health and performance challenges in the era of human enhancement : insights from sport medicine professionals
Ke Hu, Mark R. Hutchinson, Emin Ergen, Norbert Bachl, Petra Zupet, Bertrand Fincoeur, Anca Ionescu, Borja Muniz-Pardos, Andrea Petroczi, Yannis Pitsiladis, 2025, izvirni znanstveni članek

Opis: Background In the pursuit of sporting success, some elite athletes prioritise peak performance over long-term health, frequently resulting in significant and enduring health consequences. The Enhanced Games (TEG) position themselves as a bold experiment in transhumanism, advocating for the use of performance-enhancing drugs (PEDs), including methods banned by World Anti-Doping Agency (WADA), to push the boundaries of human athletic potential. Objectives The aim of this study is to explore the perspectives of sport physicians, sport scientists, physiotherapists and other allied healthcare professionals on treating and supporting “enhanced athletes”, with the view of informing future guidelines. Methods Participants were invited via email and personal contacts within sport medicine communities to complete a brief anonymous survey via QuestionPro™. Descriptive statistics were performed using Excel™ and RStudio™. Results A total of 323 healthcare professionals responded (82% were sport physicians), among whom 74% expressed a willingness to treat acute lesions and/or chronic diseases in “enhanced athletes”. In comparison, a considerable minority (30%) expressed support for assisting athletes in their use of PEDs and methods under medically supervised conditions, with high consistency across professional roles. A relatively high readiness was observed in sport physicians treating acute (77% versus 58%; p < 0.01) and chronic (75% versus 63%; p = 0.11) diseases for “enhanced athletes”. As far as WADA rules and/or national anti-doping laws apply, this support presupposes compliance with the code and the respective national laws to protect physicians from serious professional, legal and personal consequences. Conclusion The preliminary findings align with the broader goal of fostering a sport culture that values both peak performance and the short- and long-term health of all participants. These results emphasise the necessity of implementing professional guidelines and comprehensive support systems designed to safeguard the long-term well-being of all athletes and underscore the urgent need for further research into the impact of TEG on sport and its community.
Ključne besede: sport, health, performance
Objavljeno v RUP: 23.02.2026; Ogledov: 646; Prenosov: 2
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