| Title: | Differences in physical function across dementia subtypes and cognitive decline : a cross-sectional study |
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| Authors: | ID Batič, Kristina (Author) ID Kozinc, Žiga (Author) ID Rus Prelog, Polona (Author) |
| Files: | https://www.pagepressjournals.org/bam/article/view/13726/13125
RAZ_Batic_Kristina_2025.pdf (278,81 KB) MD5: 54BB7FCDBE9D505E74371DF6FFF75E18
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| Language: | English |
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| Work type: | Article |
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| Typology: | 1.01 - Original Scientific Article |
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| Organization: | FVZ - Faculty of Health Sciences
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| Abstract: | Cognitive impairment significantly affects physical function in dementia patients, but variations across dementia types and levels of cognitive decline remain unclear. This retrospective cross-sectional study included 874 patients (80.75 ± 8.00 years; 60.4% female) with different dementia types and cognitive impairment levels. Six physical function tests were admisterd: the De Morton Mobility Index (DEMMI), 6-minute walking test (6MTW), 10-meter walking test (10MWT), hand grip strength (HGS), 30-second chair stand (30sSTS), and the timed “Up & Go” test (TUG). Cognitive function was assessed using the Mini-Mental State Examination (MMSE). The Mild Cognitive Imapirment (MCI) group outperformed Alzheimer's Dementia (AD) and Vascular Dementia (VaD) on DEMMI, 30sSTS and HGS (p < 0.001, η² = 0.012 to 0.052). Differences in the 6MWT were significant in ANOVA but disappeared after adjusting for sex and age (p = 0.066). Severe cognitive impairment was linked to significantly lower physical performance across all measures (p < 0.001, η² = 0.037 to 0.064). Physical function profiles vary by dementia type and cognitive decline level, highlighting the need for targeted interventions to address specific physical challenges. |
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| Keywords: | dementia, cognitive decline, physical function |
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| Publication status: | Published |
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| Publication version: | Version of Record |
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| Publication date: | 29.05.2025 |
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| Year of publishing: | 2025 |
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| Number of pages: | str. 228-236 |
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| Numbering: | Vol. 35, no. 3, [article no.] 13726 |
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| PID: | 20.500.12556/RUP-22678  |
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| UDC: | 796.02:616.892.3 |
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| ISSN on article: | 2037-7460 |
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| DOI: | 10.4081/ejtm.2025.13726  |
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| COBISS.SI-ID: | 238647043  |
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| Publication date in RUP: | 22.02.2026 |
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| Views: | 35 |
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| Downloads: | 0 |
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